An Exposure System for In-vitro 3D Tumour HIFU Studies

Abstract

A system for targeting, delivering and quantifying thermal exposure of 3D tumour spheroids for application in hyperthermia ± radiation studies was developed and tested An acoustic holography designed lens was used to broaden a focused ultrasound beam. Preliminary experiments demonstrate the system is fit for purpose. It is being used to compare ultrasound hyperthermia exposed spheroids with water bath heating experiments. Spheroid exposures have been completed (see figure) and the results of viability studies and comparison with water bath heat spheroids will be presented at the meeting.

@inproceedings{RivensISTU2022hyperthermia,
 author = {Noé Jiménez and Enrique M. González-Mateo and José M. Benlloch and Francisco Camarena},
 booktitle = {ISTU 2022: 21th International Symposium for Therapeutic Ultrasound. Toronto, Canada. 7 - 10 June},
 editor = {Conference proceedings},
 isbn = {ISBN: 978-84-87985-30-4},
 month = {6},
 organization = {International Society for Therapeutic Ultrasound},
 publisher = {European Focused Ultrasound Charitable Society},
 series = {Poster},
 title = {An Exposure System for In-vitro 3D Tumour HIFU Studies},
 year = {2022}
}